Etiological and Clinical Characteristics of Anterior Uveitis Cases in a Tertiary Hospital in Istanbul

INTRODUCTION: Investigation of etiological and clinical features of patients diagnosed with anterior uveitis followed in Ümraniye Training and Research Hospital, Department of Ophthalmology, Uvea Department
METHODS: Patients’ diagnosed with anterior uveitis in Ümraniye Training and Research Hospital, Department of Ophthalmology, Uvea Department between 2009 and 2011 were scanned retrospectively from patient files. Age of onset, gender, family history, ophthalmologic examination findings, laboratory findings and treatment approaches were evaluated for each case.
RESULTS: 144 eyes of 118 patients were included in the study. It was determined that 59 (50%) of the patients were male and 59 (50%) were female, and their mean age was 39.3±14.3 (minimum-maximum, 5-83) years. It was observed that 44% of the cases had idiopathic anterior uveitis. The most common diagnoses of anterior uveitis in non-idiopathic cases were HLA-B27 associated anterior uveitis and Fuchs' uveitis syndrome, with 16 patients each. Systemic disease association was detected in 22 (18%) patients, and the most common systemic disease was ankylosing spondylitis, which was detected in 8 (6.8%) patients.
DISCUSSION AND CONCLUSION: In our study, it was found that HLA-B27 associated anterior uveitis and Fuchs' uveitis syndrome are the most common anterior uveitis after idiopathic anterior uveitis. In a multidisciplinary study, it was seen that it was possible to diagnose most of the anterior uveitis cases.

Ýstanbul’daki Bir Üçüncü Basamak Hastanedeki Ön Üveit Olgularýnýn Etiyolojik ve Klinik Özellikleri

GÝRÝÞ ve AMAÇ: Ümraniye Eðitim ve Araþtýrma Hastanesi, Göz Hastalýklarý Anabilim Dalý, Üvea Biriminde takip edilen ön üveit tanýsý almýþ hastalarýn etiyolojik ve klinik özelliklerinin incelenmesi.
YÖNTEM ve GEREÇLER: Ümraniye Eðitim ve Araþtýrma Hastanesi, Göz Hastalýklarý Anabilim Dalý, Üvea Biriminde 2009-2011 yýllarý arasýnda ön üveit tanýsý almýþ hastalarýn bilgileri hasta dosyalarýndan retrospektif olarak tarandý. Her bir olgu için baþlangýç yaþý, cinsiyet, aile öyküsü, oftalmolojik muayene bulgularý, laboratuvar bulgularý ve tedavi yaklaþýmlarý deðerlendirildi.
BULGULAR: Çalýþmaya 118 hastanýn 144 gözü dahil edildi. Hastalarýn 59’unun erkek (%50) 59’unun kadýn (%50) olduðu ve ortalama yaþlarýnýn 39.3±14.3 (minimum-maksimum, 5-83) yýl olduðu saptandý. Olgularýn %44’ünün idiyopatik ön üveiti olduðu görüldü. Ýdiyopatik olmayan olgularda en sýk ön üveit tanýlarýnýn 16’þar hasta ile HLA-B27 iliþkili ön üveit ve Fuchs’ Üveit Sendromu olduðu görüldü. Sistemik hastalýk iliþkisinin 22 (%18) hastada tespit edilebildiði, en sýk görülen sistemik hastalýðýn ise 8 (%6,8) olguda tespit edilen ankilozan spondilit olduðu saptandý.
TARTIÞMA ve SONUÇ: Çalýþmamýzda HLA-B27 iliþkili ön üveit ve Fuchs’ Üveit Sendromunun idiyopatik ön üveit sonrasý en sýk görülen ön üveitler olduðu saptanmýþtýr. Multidisipliner bir çalýþma ile ön üveit olgularýn çoðunda taný koymanýn mümkün olduðu görülmüþtür.