Kocaeli Med J. 2021; 10(1): 1-6 | DOI: 10.5505/ktd.2021.10437

Comparison of Neutrophil / Lymphocyte Ratio, Vitamin B12 and Vitamin D Levels in Patients With Fibromyalgia and Myofascial Pain Syndrome

Kaðan Özkuk¹, Bilal Uysal^2
1Department Of Medical Ecology And Hydroclimatology, Usak University Faculty Of Medicine, Usak, Turkey
²Department Of Physical Medicine And Rehabilitation, Balýkesir Physical Medicine And Rehabilitation Training And Research Hospital, Balýkesir, Turkey

INTRODUCTION: This study aimed to compare the biomarkers in patients presenting with chronic pain due to Fibromyalgia (FMS) and Myofascial Pain Syndrome (MAS), especially in differential diagnosis
METHODS: This study was planned as a retrospective study. The complete blood count test, vitamin B12 (cobalamin) and 25 (OH) D vitamin values of 105 patients with FMS and 109 MAS were compared.
RESULTS: There was a statistically significant difference in 25 (OH) vitamin D in the comparison between the groups. When 25 (OH) vitamin D was deficient, inadequate and categorized as normal, no statistically significant difference was found.
DISCUSSION AND CONCLUSION: FMS and MAS are common musculoskeletal disorders. In our study, we found no significant difference between FMS and MAS groups in laboratory parameters. Although examinations are performed to exclude other diseases, these tests may be insufficient in the diagnosis process and in making a differential diagnosis between the two diseases.

Keywords: Fibromyalgia, Myofascial Pain Syndrome, Neutrophil / Lymphocyte Ratio, Vitamin B12, Vitamin D

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Fibromiyalji ve Miyofasyal Aðrý Sendromlu Hastalarýn Nötrofil/Lenfosit Oraný, B12 Vitamin ve D Vitamin Düzeyleri Açýsýndan Karþýlaþtýrýlmasý

Kaðan Özkuk¹, Bilal Uysal^2
1Uþak Üniversitesi Týp Fakültesi, Týbbi Ekoloji ve Hidroklimatoloji Anabilim Dalý, Uþak, Türkiye
²Balýkesir Üniversitesi Týp Fakültesi Fiziksel Týp ve Rehabilitasyon Anabilim Dalý, Balýkesir, Türkiye

GÝRÝÞ ve AMAÇ: Fibromiyalji(FMS) Ve Miyofasyal Aðrý Sendromuna (MAS) baðlý kronik aðrý nedeniyle baþvuran hastalarda özellikle ayýrýcý tanýya yardýmcý olabilecek biyobelirteçleri karþýlaþtýrmak.
YÖNTEM ve GEREÇLER: Bu çalýþma retrospektif olarak planlandý. Hastane hasta dosyalarý incelenerek 105 FMS ve 109 MAS tanýlý kadýn hastanýn tam kan sayýmý testi, B12 vitamini (kobalamin) ve 25(OH) D vitamin deðerleri karþýlaþtýrýldý.
BULGULAR: Gruplar arasý karþýlaþtýrmada 25(OH)D vitamini düzeylerinde istatistiksel olarak anlamlý fark varken diðer deðiþkenlere ait verilerde istatistiksel anlamlý fark yoktu. Ýki grup arasýnda 25(OH)D vitaminini eksiklik, yetersiz ve normal olarak kategorize edildiðinde istatistiksel olarak anlamlý fark saptanmadý.
TARTIÞMA ve SONUÇ: FMS ve MAS yaygýn görülen kas iskelet sistemi hastalýklarýdýr. Çalýþmamýzda, laboratuvar parametrelerinde FMS ve MAS gruplarý arasýnda belirgin fark saptamadýk. Diðer hastalýklarý dýþlamak için tetkikler yapýlsa da tanýda koyma sürecinde ve iki hastalýk arasýnda ayýrýcý taný yapmada bu tetkiklerin yetersiz kalabilmektedir.

Anahtar Kelimeler: Fibromiyalji, Miyofasyal Aðrý Sendromu, Nötrofil / Lenfosit Oraný, B12 Vitamin, D Vitamin

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