Serviste Takip Edilen Covidli Gebelerle Yoðunbakýmda Tedavisi Yapýlan Covidli Gebelerin Laboratuvar Parametrelerinin ve Perinatal Sonuçlarýnýn Karþýlaþtýrýlmasý

GÝRÝÞ ve AMAÇ: Covid 19 ilk olarak Aralýk 2019’da Çin’in Wuhan kentinde tanýmlanmýþ ve hýzla yayýlarak pandemi haline gelmiþtir. Bu çalýþmada Covid19 pozitif tanýsý alýp serviste yatarak tedavi olmuþ gebelerle Covid 19 pozitif olup yoðunbakým ihtiyacý olan gebelerin laboratuvar parametrelerindeki farklýlýklarýn saptanmasý, her iki grubun perinatal sonuçlarýnýn karþýlaþtýrmasý amaçlanmýþtýr.
YÖNTEM ve GEREÇLER: Çalýþma Mart 2020 ve Haziran 2021 tarihleri arasýnda kadýn doðum kliniðinde yatýrýlan 134 Covid 19 pozitif gebenin datalarýnýn retrospektif olarak taranmasýyla gerçekleþtirilmiþtir. Bu iki grup hastanýn Covid pozitif tanýsý alýp yatýþ kararý verildiðinde bakýlan laboratuvar parametreleri ve perinatal sonuçlarý karþýlaþtýrýlmýþtýr.
BULGULAR: Bu iki gruba bakýldýðýnda; yoðunbakýma yatýrýlan hastalarýn lenfosit (Ly) (p<0,001), üre (p<0,001) ve D-dimer (p=0,01) deðerleri anlamlý düzeyde düþük, glukoz (p<0,001), alanin aminotransferaz (ALT) (p<0,001), aspartat aminotransferaz (AST) (p<0,001), total protein (p<0,001), albümin (p=0,001), C reaktif protein (CRP) (p<0,001), ferritin (p<0,001) ve prokalsitonin (p<0,001) düzeylerinin anlamlý derecede yüksek olduðu görülmüþtür. Yine iki grubun perinatal sonuçlarý karþýlaþtýrýldýðýnda yoðunbakýma yatan hastalarda gravide deðeri (p=0,028), ek hastalýk görülme oraný (p=0,006) anlamlý derecede yüksek iken, medyan gebelik haftasýnýn anlamlý derecede düþük olduðu görülmüþtür (p<0,001).
TARTIÞMA ve SONUÇ: Yoðunbakým ihtiyacý olan Covid pozitif gebelerin laboratuvar parametrelerinde hastaneye ilk yatýþta bile farklýlýklar görülebilir. Ayrýca perinatal sonuçlar açýsýndan bakýldýðýnda yoðunbakým ihtiyacý olan gebelerde mortalite ve morbidite daha yüksek olabilir.

Comparison of Laboratory Parameters and Perinatal Results of Pregnant Women with Covid who Were Followed up in the Service and those with Covid who Were Treated in the Intensive Care Unit

INTRODUCTION: Covid 19 was first seen and identified in Wuhan, China in December 2019, and within a few months it quickly spread all over the world and became a pandemic.In this study, we aimed to determine the differences in laboratory parameters of pregnant women who were hospitalized in the ward and those who needed intensive care, and to compare the perinatal results between the two groups
METHODS: This study was carried out by retrospectively scanning the data of 134 Covid positive pregnant women hospitalized in the gynecology clinic March 2020 and June 2021.When these two groups of patients were diagnosed as Covid positive and decided to be admitted to the ward, laboratory parameters and perinatal results were compared.
RESULTS: Looking at these two groups, lymphocyte (Ly), urea (p<0.001), D-dimer (p=0.01), glucose (p<0.001), alanine aminotransferase (ALT) (p<0.001), aspartate aminotransferase (AST) (p<0.001), total protein (p< 0.001), albumin (p=0.001), C reactive protein (CRP) (p<0.001), ferritin (p<0.001) and procalcitonin (p<0.001) levels were significantly higher. Again, when the perinatal results of the two groups were compared, the gravide value (p=0.028), the incidence rate of additional diseases (pOctober0.006) were significantly higher in patients admitted to intensive care, while the median week of pregnancy was significantly lower (p<0.001).
DISCUSSION AND CONCLUSION: There may be differences in the laboratory parameters of Covid positive pregnant women who need intensive care, even at first hospitalization. Also, in terms of perinatal outcomes, morbidity and mortality may be higher in pregnant women who need intensive care.